Improved 11α-hydroxycanrenone production by modification of cytochrome P450 monooxygenase gene in Aspergillus ochraceus
نویسندگان
چکیده
منابع مشابه
Ochratoxin production by the Aspergillus ochraceus group and Aspergillus alliaceus.
Ochratoxin A is a toxic and carcinogenic fungal secondary metabolite; its presence in foods is increasingly regulated. Various fungi are known to produce ochratoxins, but it is not known which species produce ochratoxins consistently and which species cause ochratoxin contamination of various crops. We isolated fungi in the Aspergillus ochraceus group (section Circumdati) and Aspergillus alliac...
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The results of a limited number of studies on echinoderms provide evidence for the presence of a cytochrome P450 monooxygenase system in representatives of three classes of the phylum Echinodermata: the asteroids (sea stars), holothuroids (sea cucumbers) and echinoids (sea urchins). The monooxygenase system has been demonstrated to be involved in the metabolism of xenobiotic compounds, but is a...
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Phytoalexins are low molecular weight antimicrobial compounds that are synthesized in response to pathogen attack. The phytoalexin camalexin, an indole derivative, is produced by Arabidopsis in response to infection with the bacterial pathogen Pseudomonas syringae. The phytoalexin deficient 3 ( pad3 ) mutation, which causes a defect in camalexin production, has no effect on resistance to P. syr...
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Insecticide resistance is one of the major obstacles to the control of agriculturally important arthropod pests. Resistance results in increased application frequencies, increased dosages, decreased yields, environmental damage, and outbreaks of human and animal diseases when vectors cannot be controlled. The World Health Organization has called insecticide resistance "the biggest single obstac...
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BACKGROUND Bioethanol production from sustainable sources of biomass that limit effect on food production are needed and in a biorefinery approach co-products are desirable, obtained from both the plant material and from the microbial biomass. Fungal biotransformation of steroids was among the first industrial biotransformations allowing corticosteroid production. In this work, the potential of...
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ژورنال
عنوان ژورنال: Acta Pharmaceutica
سال: 2020
ISSN: 1846-9558
DOI: 10.2478/acph-2021-0004